These are medications for which chest pain appears among the most-reported events in FDA adverse event reports. A report does not mean the drug caused the event. Report counts largely reflect how widely a drug is used and how often events are reported; they cannot be used to compare or rank drugs by risk. This list shows drugs where this event is among their top reported reactions, not every drug ever associated with it. This information is not medical advice. Do not stop or change a medication based on this data; discuss any concerns with your healthcare provider. Data from the FDA Adverse Event Monitoring System (AEMS), formerly FAERS, via OpenFDA.

Pain or discomfort anywhere in the chest, which can feel sharp, dull, tight, or like pressure. It can stem from the heart, lungs, muscles, or digestive system, and it is always worth taking seriously and discussing with a doctor. In adverse event reports, it covers reported chest pain of any type or severity. Full definition in the glossary →

341 drugs meet the threshold; showing the 100 most-reported.

Medications with FDA adverse event reports of chest pain, by report count
DrugReports of this event% of drug's total reports
Ecotrin12,0262.4%
Bayer Low Dose11,8742.4%
Aspirin11,8522.4%
Bayer Genuine Aspirin11,8452.4%
Bayer11,8442.4%
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange11,8422.4%
Bayer Aspirin Regimen Enteric Coated11,8412.4%
Bufferin Regular Strength Pain Relief11,8412.4%
Ecotrin Regular Strength11,8412.4%
Tri-buffered Aspirin11,8412.4%
Lasix7,6161.9%
Vitamin D7,5592.0%
Prinivil6,0262.0%
Zestril6,0262.0%
Synthroid5,9492.2%
Omeprazole5,9081.7%
Lisinopril5,6481.9%
Qbrelis5,6481.9%
Pantoprazole Sodium5,5692.3%
Protonix5,5692.3%
Plavix5,2942.7%
Lipitor5,1732.1%
Zocor5,1702.1%
Metoprolol5,1622.1%
Metoprolol Tartrate5,1622.1%
Advil4,6502.0%
Albuterol4,5502.3%
Motrin Infants4,4802.1%
Katerzia4,3211.6%
Norliqva4,3211.6%
Sdamlo4,3211.6%
Furosemide4,3031.7%
Lasix Onyu4,3031.7%
Prevacid4,2862.5%
Ativan4,1982.4%
Advil Liqui-gels4,0472.0%
Pantoprazole4,0232.1%
Motrin Ib4,0102.0%
Nexium4,0012.2%
Advil Migraine3,9812.0%
Ibuprofen3,9802.0%
Caldolor3,9792.0%
Motrin Ib Migraine3,9792.0%
Crestor3,9072.0%
Protonix Delayed-release3,8712.7%
Letairis3,8233.1%
Simvastatin3,7961.9%
Xanax XR3,6181.8%
Xanax3,6091.8%
Tylenol Cold Plus Head Congestion Severe3,6012.3%
Celebrex3,5002.7%
Ventolin HFA3,3721.9%
ProAir HFA3,2842.8%
Ag-x3,2602.2%
Altace3,2312.7%
Ramipril3,2312.7%
Losartan Potassium3,1471.9%
Norvasc3,1272.2%
Naproxen3,1183.6%
Tenormin3,0212.3%
Hydrochlorothiazide3,0042.1%
Inzirqo3,0042.1%
Microzide3,0042.1%
Coreg2,9892.3%
Klonopin2,9581.9%
Bisoprolol2,8782.2%
Prevacid 24 Hr2,8652.4%
Prevacid Solutab2,8362.7%
Lansoprazole2,8352.7%
Aldactone2,8092.1%
Nitrostat2,7955.7%
Atenolol2,7872.3%
Singulair2,7522.3%
Levoxyl2,6632.3%
Loreev XR2,6592.1%
Lorazepam2,6582.1%
Benadryl2,5822.8%
Euthyrox2,4922.3%
Opsumit2,4543.6%
Nitrolingual2,4175.9%
Adcirca2,4123.3%
Nitro-dur2,4076.0%
Spiriva2,3751.8%
Spiriva Handihaler2,3741.8%
Klor-con2,3732.2%
Naprosyn2,3693.1%
Coumadin2,3631.9%
Warfarin Sodium2,3631.9%
Tirosint2,3562.3%
Tirosint Sol2,3562.3%
Nitro-bid2,3526.0%
Nitroglycerin In Dextrose2,3336.0%
Nitroglycerin Lingual2,3326.0%
Glonoinum2,3316.0%
Nitro-time2,3316.0%
Nitroglycerin2,3316.0%
Nitroglycerin Transdermal Infusion System2,3316.0%
Rectiv2,3315.9%
Clopidogrel2,3202.3%
Unithroid2,2902.3%

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