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Weight Loss (Weight Decreased): Drugs With FDA Adverse Event Reports

659 medications where weight loss is among the most-reported events, ranked by number of reports.

These are medications for which weight loss appears among the most-reported events in FDA adverse event reports. A report does not mean the drug caused the event. Report counts largely reflect how widely a drug is used and how often events are reported; they cannot be used to compare or rank drugs by risk. This list shows drugs where this event is among their top reported reactions, not every drug ever associated with it. This information is not medical advice. Do not stop or change a medication based on this data; discuss any concerns with your healthcare provider. Data from the FDA Adverse Event Monitoring System (AEMS), formerly FAERS, via OpenFDA.

Losing body weight without deliberately trying to. It can happen gradually or quickly, and reports range from modest changes to significant unintended loss. In adverse event reports, it reflects weight loss the patient or clinician considered noteworthy. Full definition in the glossary →

659 drugs meet the threshold; showing the 100 most-reported.

Medications with FDA adverse event reports of weight loss, by report count
DrugReports of this event% of drug's total reports
Deltasone16,7953.4%
Prednisone16,7953.4%
Prednisone Delayed Release16,7953.4%
Ecotrin12,9002.5%
Humira12,7931.8%
Bayer Low Dose12,7452.5%
Aspirin12,7162.5%
Bayer Genuine Aspirin12,7152.5%
Bayer12,7082.5%
Bayer Aspirin Regimen Enteric Coated12,7072.5%
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange12,7062.5%
Bufferin Regular Strength Pain Relief12,7062.5%
Ecotrin Regular Strength12,7062.5%
Tri-buffered Aspirin12,7062.5%
Vitamin D12,3573.3%
Tylenol Extra Strength12,2703.0%
Metformin Hydrochloride12,1313.5%
Glucophage12,1303.5%
Byetta12,12523.2%
Tylenol Regular Strength11,8343.0%
Methotrexate11,1422.3%
Metformin10,7683.7%
Rasuvo10,0952.5%
Trexall10,0782.5%
Otrexup10,0762.5%
Jylamvo10,0662.5%
Xatmep10,0662.5%
Lasix9,7722.5%
Synthroid8,9213.2%
Rapidol8,8913.0%
Medline8,6122.8%
Neurontin8,5272.4%
Omeprazole8,2682.4%
Pantoprazole Sodium8,0973.3%
Protonix8,0973.3%
Prinivil8,0172.7%
Zestril8,0152.7%
Folic Acid8,0003.3%
Venexa8,0003.3%
Vitrexyl8,0003.3%
Tylenol Extra Strength Caplet7,9103.0%
Qbrelis7,7262.7%
Lisinopril7,7242.6%
Panadol7,5253.0%
Panadol Extra Strength7,5253.0%
Excedrin Rapid Relief7,5223.0%
Tylenol 8 Hr Arthritis Pain7,4843.0%
Tylenol 8hr7,4733.0%
Childrens Tylenol7,4543.0%
Acetaminophen7,4493.0%
Infants Tylenol7,4473.0%
Feverall7,4463.0%
Feverall Childrens7,4463.0%
Feverall Infants7,4463.0%
Feverall Jr. Strength7,4463.0%
Pharbetol7,4463.0%
Dolo-neurobion7,4443.0%
M-pap7,4443.0%
Midol Long Lasting Relief7,4443.0%
Tylenol For Children Plus Adults7,4443.0%
Remicade7,2033.4%
Gralise6,9102.4%
Gabapentin6,8522.4%
Gabarone6,8522.4%
Lipitor6,8472.8%
Metoprolol6,5322.6%
Metoprolol Tartrate6,5322.6%
Lyrica6,2352.3%
Katerzia6,0662.3%
Norliqva6,0662.3%
Sdamlo6,0662.3%
Zocor5,8412.4%
Furosemide5,8082.3%
Lasix Onyu5,8082.3%
Pantoprazole5,7163.0%
Tylenol Cold Plus Head Congestion Severe5,5193.5%
Ag-x5,4243.7%
Xanax XR5,4092.7%
Xanax5,3912.7%
Crestor5,3012.7%
Entresto5,1914.5%
Ativan5,1782.9%
Otezla4,9923.5%
Lantus4,9773.4%
Revlimid4,9351.2%
Advil4,9302.1%
Ventolin HFA4,7422.7%
Motrin Infants4,7282.2%
Klonopin4,7163.0%
Simvastatin4,6532.3%
Protonix Delayed-release4,6523.2%
Losartan Potassium4,6372.7%
Benadryl4,5184.9%
Albuterol4,4562.3%
Maxidex4,4151.5%
Ozurdex4,3931.5%
Dexamethasone4,3911.5%
Dextenza4,3911.5%
Dexycu4,3911.5%
Hemady4,3911.5%

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