These are medications for which constipation appears among the most-reported events in FDA adverse event reports. A report does not mean the drug caused the event. Report counts largely reflect how widely a drug is used and how often events are reported; they cannot be used to compare or rank drugs by risk. This list shows drugs where this event is among their top reported reactions, not every drug ever associated with it. This information is not medical advice. Do not stop or change a medication based on this data; discuss any concerns with your healthcare provider. Data from the FDA Adverse Event Monitoring System (AEMS), formerly FAERS, via OpenFDA.

Difficulty passing stool, or having fewer bowel movements than usual. Full definition in the glossary →

465 drugs meet the threshold; showing the 100 most-reported.

Medications with FDA adverse event reports of constipation, by report count
DrugReports of this event% of drug's total reports
Ecotrin11,0362.2%
Revlimid10,9642.6%
Bayer Low Dose10,8792.2%
Aspirin10,8512.2%
Bayer Genuine Aspirin10,8492.2%
Bayer10,8432.2%
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange10,8412.2%
Bayer Aspirin Regimen Enteric Coated10,8412.2%
Bufferin Regular Strength Pain Relief10,8412.2%
Ecotrin Regular Strength10,8412.2%
Tri-buffered Aspirin10,8412.2%
Vitamin D10,0472.7%
Tylenol Extra Strength9,8302.4%
Tylenol Regular Strength9,3952.4%
Lasix7,9522.0%
Neurontin7,8742.2%
Omeprazole7,5522.2%
Synthroid7,0412.5%
Maxidex6,7952.4%
Hemady6,7902.4%
Dexamethasone6,7882.4%
Dextenza6,7882.4%
Dexycu6,7882.4%
Ozurdex6,7882.3%
Gralise6,6032.3%
Gabapentin6,5562.3%
Gabarone6,5562.3%
Glucophage6,3611.8%
Metformin Hydrochloride6,3611.8%
Pantoprazole Sodium5,7872.4%
Protonix5,7872.4%
Prinivil5,6741.9%
Zestril5,6741.9%
Metformin5,5071.9%
Lisinopril5,4821.9%
Qbrelis5,4821.9%
Katerzia5,3902.0%
Norliqva5,3902.0%
Sdamlo5,3902.0%
Furosemide5,1712.0%
Lasix Onyu5,1712.0%
Lyrica5,1371.9%
Zocor4,8902.0%
Miralax4,7875.4%
Metoprolol4,7271.9%
Metoprolol Tartrate4,7271.9%
Lipitor4,6111.9%
Ondansetron4,5923.9%
Tylenol Cold Plus Head Congestion Severe4,5152.9%
Crestor4,4802.3%
Xanax XR4,4362.2%
Xanax4,4202.2%
Ativan4,3272.5%
Pantoprazole4,1792.2%
Oxycodone Hydrochloride4,1202.3%
Albuterol4,1032.1%
Ozempic4,0536.4%
Zofran4,0053.8%
Ag-x3,9942.7%
Simvastatin3,9322.0%
Losartan Potassium3,7352.2%
OxyContin3,7071.8%
Norvasc3,5732.5%
Klonopin3,4292.2%
Mounjaro3,3023.8%
Mounjaro Kwikpen3,3023.8%
Protonix Delayed-release3,2412.2%
Vitamin C Serum3,2073.6%
Aloprim3,1912.1%
Zyloprim3,1912.1%
Allopurinol3,1902.1%
Aimovig3,1795.9%
Hydrochlorothiazide3,0602.1%
Inzirqo3,0602.1%
Microzide3,0602.1%
Ms Contin3,0602.6%
Colace3,0546.0%
Levoxyl3,0512.7%
Prevacid3,0341.8%
Cymbalta3,0072.2%
ProAir HFA2,9412.5%
Euthyrox2,9282.7%
Loreev XR2,9232.3%
Lorazepam2,9222.3%
Klor-con2,9042.7%
Zovirax2,8822.6%
Nexium2,8531.6%
Plavix2,8231.4%
Tirosint Sol2,8122.8%
Tirosint2,8112.8%
Ibrance2,7793.0%
Unithroid2,7222.8%
Acyclovir2,7182.7%
Avaclyr2,7182.7%
Levo-t2,7112.8%
Ermeza2,7002.8%
Levothyroxine Sodium2,7002.8%
Thyquidity2,7002.8%
Seroquel XR2,6671.6%
Pomalyst2,6292.6%

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