These are medications for which muscle spasms appears among the most-reported events in FDA adverse event reports. A report does not mean the drug caused the event. Report counts largely reflect how widely a drug is used and how often events are reported; they cannot be used to compare or rank drugs by risk. This list shows drugs where this event is among their top reported reactions, not every drug ever associated with it. This information is not medical advice. Do not stop or change a medication based on this data; discuss any concerns with your healthcare provider. Data from the FDA Adverse Event Monitoring System (AEMS), formerly FAERS, via OpenFDA.

Sudden, involuntary tightening of a muscle, often called cramps. Full definition in the glossary →

194 drugs meet the threshold; showing the 100 most-reported.

Medications with FDA adverse event reports of muscle spasms, by report count
DrugReports of this event% of drug's total reports
Vitamin D9,3152.5%
Ecotrin8,0861.6%
Bayer Low Dose7,9821.6%
Bayer7,9641.6%
Aspirin7,9631.6%
Bayer Genuine Aspirin7,9631.6%
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange7,9571.6%
Bayer Aspirin Regimen Enteric Coated7,9571.6%
Bufferin Regular Strength Pain Relief7,9571.6%
Ecotrin Regular Strength7,9571.6%
Tri-buffered Aspirin7,9571.6%
Revlimid7,6511.8%
Neurontin6,5071.8%
Forteo5,7385.1%
Lipitor5,6552.3%
Synthroid5,5702.0%
Prinivil5,2201.7%
Zestril5,2201.7%
Gralise5,1921.8%
Gabapentin5,1401.8%
Gabarone5,1401.8%
Crestor5,0742.6%
Lisinopril5,0591.7%
Qbrelis5,0591.7%
Omeprazole5,0431.5%
Lyrica4,6411.7%
Zocor4,3331.8%
Ag-x4,0702.8%
Katerzia3,8141.5%
Norliqva3,8141.5%
Sdamlo3,8141.5%
Baclofen (intrathecal)3,3333.9%
Simvastatin3,3041.6%
Lioresal (baclofen)3,2333.9%
Lyvispah3,2323.9%
Baclofen3,2313.9%
Fleqsuvy3,2313.9%
Ozobax DS3,2313.9%
Repatha3,2092.0%
Tysabri3,1921.8%
Losartan Potassium2,9601.7%
Klonopin2,9511.9%
Vitamin C Serum2,7633.1%
Avonex2,4611.7%
Cymbalta2,4531.8%
Hydrochlorothiazide2,4391.7%
Inzirqo2,4391.7%
Microzide2,4391.7%
ParaGard T 380A2,4205.7%
Omegaven2,3802.7%
Norvasc2,2391.6%
Valium2,1641.8%
Prolia2,1571.3%
Tenormin2,1391.6%
Euthyrox2,1251.9%
Tecfidera2,1251.7%
Clonazepam2,0541.8%
Levoxyl2,0521.8%
Atenolol1,9911.6%
Zetia1,9392.7%
Tirosint1,8261.8%
Tirosint Sol1,8261.8%
Zovirax1,8181.6%
Imbruvica1,7652.2%
Ezallor Sprinkle1,7492.2%
Rosuvastatin1,7492.2%
Acyclovir1,7341.7%
Avaclyr1,7341.7%
Levo-t1,7261.8%
Cipro1,7061.8%
Topamax1,6721.9%
Prilosec1,6391.5%
Zoloft1,5971.5%
Ampyra1,5942.2%
Flonase1,5571.7%
Flovent1,5571.7%
Pomalyst1,5131.5%
Claritin Reditabs1,5121.5%
Gilenya1,5091.8%
Claritin Liqui-gels1,5061.5%
Claritin1,5041.5%
Claritin Allergy1,5041.5%
Aimovig1,5032.8%
Ambien CR1,4831.8%
Atorvastatin Calcium1,4432.1%
Ambien1,4211.7%
Cozaar1,3641.8%
Flexeril1,3412.8%
Ciprofloxacin1,3151.7%
Miralax1,2811.4%
Meloxicam1,2792.3%
Mobic1,2792.3%
Toprol XL1,2611.5%
Ciprofloxacin In Dextrose1,2511.8%
Ciprofloxacin Otic1,2511.8%
Ferrum Metallicum1,2391.9%
Pulmicort1,1812.1%
Rhinocort1,1812.1%
Ocrevus1,0571.7%
Xyrem1,0331.7%

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