Equetrocarbamazepine
According to the FDA label: EQUETRO is: A mood stabilizer indicated for the treatment of acute manic or mixed episodes associated with bipolar I disorder ( 1.1 ) Indicated for the treatment of the pain associated with trigeminal neuralgia ( 1.2 ) An anti-epileptic drug (AED) indicated for the treatment of partial seizures with complex symptomatology, generalized tonic-clonic seizures, and mixed seizures ( 1.3 ) 1.1Acute Manic or Mixed Episodes associated with Bipolar I Disorder EQUETRO is indicated for treatment of…
35,716 adverse event reports submitted to the FDA (2001–2026)
Top Reported Adverse Events
The most frequently reported events in association with Equetro in the FAERS database. These are events reported by patients taking this medication, not necessarily caused by it. A single report may include multiple events.
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Drug Ineffective 3,438 reports
A report that the medication did not work as expected for the person taking it. This is a reporting category, not a sign the drug is defective. It simply means someone felt it was not helping their condition.
Full definition in the glossary →Drug Interaction 2,417 reports
A report that two or more medications may have affected each other when taken together.
Full definition in the glossary →Toxicity to Various Agents 2,238 reports
A broad reporting category used when the body has a harmful response, sometimes involving more than one substance.
Full definition in the glossary →Seizure 1,929 reports
A sudden burst of electrical activity in the brain that can cause shaking, altered awareness, or other temporary changes.
Full definition in the glossary →Fall 1,842 reports
A report that the person fell down. Falls are tracked because they can signal issues like dizziness, weakness, or balance problems.
Full definition in the glossary →Off Label Use 1,789 reports
Using a medication for a condition or in a way that the FDA has not officially approved. This is common and often legal, and a report of it does not mean something went wrong. Doctors sometimes prescribe drugs off label based on their judgment.
Full definition in the glossary →Dizziness 1,471 reports
A feeling of being lightheaded, unsteady, or like the room is spinning.
Full definition in the glossary → See all drugs reporting this event →Pain 1,368 reports
A general report of physical discomfort, used when no more specific location is given.
Full definition in the glossary →Fatigue 1,361 reports
Extreme tiredness or lack of energy that does not improve with rest.
Full definition in the glossary → See all drugs reporting this event →Pyrexia 1,353 reports
The medical term for fever, meaning a raised body temperature.
Full definition in the glossary → See all drugs reporting this event →Condition Aggravated 1,223 reports
A report that the person's existing health condition got worse. This describes a worsening of something the person already had, not necessarily a new problem caused by the drug.
Full definition in the glossary →Somnolence 1,201 reports
Drowsiness or strong sleepiness.
Full definition in the glossary → See all drugs reporting this event →Nausea 1,192 reports
The feeling of sickness in your stomach that often comes before vomiting.
Full definition in the glossary → See all drugs reporting this event →Rash 1,178 reports
An area of irritated, red, or bumpy skin.
Full definition in the glossary → See all drugs reporting this event →Hypotension 1,148 reports
Ranked by frequency of reports, not severity. The most-reported event is not necessarily the most dangerous or the most common in patients taking this drug.
Who Is Reporting
Demographics of patients in FAERS reports that included this information. Not all reports include patient demographics.
By Sex
View reporter sex data as a table
| Sex | Reports |
|---|---|
| Female | 17,891 |
| Male | 13,414 |
| Unknown | 170 |
By Age Group
View age group data as a table
| Age group | Reports |
|---|---|
| 0-17 | 3,048 |
| 18-34 | 4,862 |
| 35-49 | 5,628 |
| 50-64 | 5,990 |
| 65-74 | 3,155 |
| 75+ | 2,665 |
This shows who filed reports, reflecting who takes this drug and who tends to report, not who is at greatest risk.
Reported Outcomes
Outcomes recorded in FAERS reports that included Equetro. A single report may involve multiple reactions, each with a different outcome. These categories are defined by FDA reporting guidelines, not by PillSignal.
View outcome data as a table
| Outcome | Reports |
|---|---|
| Other Serious | 20,611 |
| Hospitalization | 14,226 |
| Non-Serious | 4,105 |
| Death | 3,765 |
| Life-Threatening | 2,354 |
| Disability | 963 |
Serious outcomes are far more likely to be reported than mild ones, so this overstates how often outcomes are serious. A recorded death does not mean the drug caused it.
Report Volume Over Time
Number of FAERS reports received per quarter for Equetro. Changes in volume may reflect shifts in prescribing rates, media attention, or reporting behavior, not changes in the medication's safety profile.
View report trend as a table
| Year | Reports |
|---|---|
| 2001 | 1 |
| 2002 | 4 |
| 2003 | 1 |
| 2004 | 607 |
| 2005 | 772 |
| 2006 | 773 |
| 2007 | 683 |
| 2008 | 900 |
| 2009 | 1,035 |
| 2010 | 965 |
| 2011 | 1,195 |
| 2012 | 1,379 |
| 2013 | 1,125 |
| 2014 | 1,267 |
| 2015 | 1,654 |
| 2016 | 1,857 |
| 2017 | 2,002 |
| 2018 | 2,762 |
| 2019 | 2,591 |
| 2020 | 2,185 |
| 2021 | 2,604 |
| 2022 | 2,401 |
| 2023 | 2,111 |
| 2024 | 2,083 |
| 2025 | 2,199 |
| 2026 (partial) | 560 |
The steep increase around 2004 reflects the FDA's move to electronic submission, not a change in this drug's safety. Trends track reporting volume, not risk.
Medications commonly reported with Equetro
In FDA adverse event reports that mention Equetro, these medications appeared most often in the same report.
- Levetiracetam (5,590 reports)
- Levetiracetam In (4,811 reports)
- Lamotrigine (3,751 reports)
- Gabapentin (3,370 reports)
- Lamotirigine (3,351 reports)
This reflects co-occurrence in submitted reports, not evidence of drug interaction or combined risk. People often report several medications taken for the same condition or for unrelated reasons. Talk to a doctor or pharmacist about your specific medications.
Related Drugs
Other medications with similar adverse event profiles in FDA FAERS reports.
Data Source
This data is sourced from the FDA's Adverse Event Monitoring System (AEMS), formerly FAERS, via the OpenFDA API. PillSignal is not affiliated with the FDA.
View this data on the FDA website →Data last updated: June 2026