Yasmindrospirenone + ethinyl estradiol
24,544 adverse event reports submitted to the FDA (2004–2026)
Top Reported Adverse Events
The most frequently reported events in association with Yasmin in the FAERS database. These are events reported by patients taking this medication, not necessarily caused by it. A single report may include multiple events.
Show these terms with plain-language definitions
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Pain 8,956 reports
A general report of physical discomfort, used when no more specific location is given.
Full definition in the glossary →Injury 7,733 reports
A general report of physical harm to the body, used when no more specific type is given.
Full definition in the glossary →Pulmonary Embolism 5,824 reports
A blockage in one of the arteries of the lungs, usually caused by a blood clot. This is a serious condition that needs urgent medical care.
Full definition in the glossary →Deep Vein Thrombosis 5,605 reports
A blood clot that forms in a deep vein, usually in the leg. It can be serious if the clot travels to the lungs.
Full definition in the glossary →Anxiety 4,643 reports
A feeling of worry, nervousness, or unease.
Full definition in the glossary → See all drugs reporting this event →Emotional Distress 4,571 reports
A report of emotional suffering such as upset, worry, or anguish. If you are struggling, the 988 Suicide and Crisis Lifeline (call or text 988 in the US) is available 24 hours a day.
Full definition in the glossary →- Cholecystitis Chronic 3,785 reports
- Cholelithiasis 2,796 reports
- Gallbladder Disorder 2,758 reports
General Physical Health Deterioration 2,321 reports
A report that the person's overall physical health declined.
Full definition in the glossary →Abdominal Pain 1,736 reports
Pain in the belly or stomach area.
Full definition in the glossary → See all drugs reporting this event →Nausea 1,647 reports
The feeling of sickness in your stomach that often comes before vomiting.
Full definition in the glossary → See all drugs reporting this event →Anhedonia 1,554 reports
A reduced ability to feel pleasure or interest in activities once enjoyed.
Full definition in the glossary →Thrombosis 1,419 reports
The formation of a blood clot inside a blood vessel.
Full definition in the glossary →Dyspnoea 1,335 reports
Shortness of breath or difficulty breathing. Also spelled dyspnea in American English.
Full definition in the glossary → See all drugs reporting this event →
Ranked by frequency of reports, not severity. The most-reported event is not necessarily the most dangerous or the most common in patients taking this drug.
Who Is Reporting
Demographics of patients in FAERS reports that included this information. Not all reports include patient demographics.
By Sex
View reporter sex data as a table
| Sex | Reports |
|---|---|
| Female | 24,301 |
| Male | 51 |
| Unknown | 18 |
By Age Group
View age group data as a table
| Age group | Reports |
|---|---|
| 0-17 | 917 |
| 18-34 | 11,526 |
| 35-49 | 5,351 |
| 50-64 | 411 |
| 65-74 | 1 |
| 75+ | 1 |
This shows who filed reports, reflecting who takes this drug and who tends to report, not who is at greatest risk.
Reported Outcomes
Outcomes recorded in FAERS reports that included Yasmin. A single report may involve multiple reactions, each with a different outcome. These categories are defined by FDA reporting guidelines, not by PillSignal.
View outcome data as a table
| Outcome | Reports |
|---|---|
| Other Serious | 13,665 |
| Hospitalization | 12,684 |
| Non-Serious | 2,755 |
| Life-Threatening | 1,099 |
| Disability | 799 |
| Death | 426 |
Serious outcomes are far more likely to be reported than mild ones, so this overstates how often outcomes are serious. A recorded death does not mean the drug caused it.
Report Volume Over Time
Number of FAERS reports received per quarter for Yasmin. Changes in volume may reflect shifts in prescribing rates, media attention, or reporting behavior, not changes in the medication's safety profile.
View report trend as a table
| Year | Reports |
|---|---|
| 2004 | 199 |
| 2005 | 284 |
| 2006 | 322 |
| 2007 | 329 |
| 2008 | 1,375 |
| 2009 | 705 |
| 2010 | 1,404 |
| 2011 | 6,764 |
| 2012 | 6,082 |
| 2013 | 3,245 |
| 2014 | 1,658 |
| 2015 | 489 |
| 2016 | 267 |
| 2017 | 163 |
| 2018 | 190 |
| 2019 | 188 |
| 2020 | 180 |
| 2021 | 127 |
| 2022 | 144 |
| 2023 | 164 |
| 2024 | 127 |
| 2025 | 101 |
| 2026 (partial) | 37 |
The steep increase around 2004 reflects the FDA's move to electronic submission, not a change in this drug's safety. Trends track reporting volume, not risk.
Medications commonly reported with Yasmin
In FDA adverse event reports that mention Yasmin, these medications appeared most often in the same report.
- Ibuprofen (3,023 reports)
- Ibupfrofen (1,985 reports)
- Levothyroxine (1,146 reports)
- Albuterol (1,112 reports)
- Omeprazole (1,035 reports)
This reflects co-occurrence in submitted reports, not evidence of drug interaction or combined risk. People often report several medications taken for the same condition or for unrelated reasons. Talk to a doctor or pharmacist about your specific medications.
Related Drugs
Other medications with similar adverse event profiles in FDA FAERS reports.
Data Source
This data is sourced from the FDA's Adverse Event Monitoring System (AEMS), formerly FAERS, via the OpenFDA API. PillSignal is not affiliated with the FDA.
View this data on the FDA website →Data last updated: June 2026