These are medications for which anxiety appears among the most-reported events in FDA adverse event reports. A report does not mean the drug caused the event. Report counts largely reflect how widely a drug is used and how often events are reported; they cannot be used to compare or rank drugs by risk. This list shows drugs where this event is among their top reported reactions, not every drug ever associated with it. This information is not medical advice. Do not stop or change a medication based on this data; discuss any concerns with your healthcare provider. Data from the FDA Adverse Event Monitoring System (AEMS), formerly FAERS, via OpenFDA.

A feeling of worry, nervousness, or unease that can range from occasional mild worry to persistent anxiety that interferes with daily life. Physical signs can include restlessness, a racing heart, or trouble concentrating. In adverse event reports, it covers reported anxiety of any degree. Full definition in the glossary →

592 drugs meet the threshold; showing the 100 most-reported.

Medications with FDA adverse event reports of anxiety, by report count
DrugReports of this event% of drug's total reports
Vitamin D10,5382.8%
Xanax XR10,2465.1%
Xanax10,2025.0%
Neurontin9,8752.8%
Tylenol Extra Strength9,6652.4%
Tylenol Regular Strength9,3212.4%
Ativan8,9465.1%
Klonopin8,8085.6%
Ecotrin8,6101.7%
Bayer Low Dose8,4981.7%
Aspirin8,4821.7%
Bayer8,4791.7%
Bayer Aspirin Regimen Enteric Coated8,4771.7%
Bayer Genuine Aspirin8,4771.7%
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange8,4761.7%
Bufferin Regular Strength Pain Relief8,4761.7%
Ecotrin Regular Strength8,4761.7%
Tri-buffered Aspirin8,4761.7%
Cymbalta8,2716.0%
Synthroid8,0932.9%
OxyContin7,7983.7%
Gralise7,6322.6%
Medline7,6112.5%
Gabapentin7,5772.6%
Gabarone7,5772.6%
Lyrica7,3622.8%
Prinivil7,2462.4%
Zestril7,2452.4%
Advil7,0343.0%
Omeprazole7,0282.1%
Motrin Infants6,9333.3%
Qbrelis6,8492.3%
Lisinopril6,8482.3%
Lasix6,5861.7%
Seroquel XR6,5764.1%
Advil Liqui-gels6,1303.1%
Albuterol6,1073.1%
Seroquel6,1064.0%
Motrin Ib6,1033.1%
Lexapro6,0854.9%
Advil Migraine6,0683.1%
Ibuprofen6,0633.1%
Caldolor6,0603.1%
Motrin Ib Migraine6,0603.1%
Truvada5,93913.2%
Zoloft5,8375.6%
Chantix5,8187.6%
Clonazepam5,7184.9%
Lorazepam5,5524.3%
Loreev XR5,5524.3%
Metformin Hydrochloride5,4621.6%
Glucophage5,4611.6%
Pantoprazole Sodium5,4052.2%
Protonix5,4052.2%
Oxycodone Hydrochloride5,3883.0%
Yaz5,26416.9%
Wellbutrin XL5,0885.8%
Valium5,0334.2%
Abilify4,9224.3%
Singulair4,7914.0%
Lipitor4,7492.0%
Metformin4,7031.6%
Fosamax4,6485.7%
Yasmin4,64318.9%
Zocor4,6301.9%
Celexa4,5944.1%
Tylenol Cold Plus Head Congestion Severe4,5652.9%
Metoprolol4,5201.8%
Metoprolol Tartrate4,5201.8%
Wellbutrin SR4,5075.8%
Ventolin HFA4,4682.6%
Mirena4,4333.3%
Katerzia4,3771.7%
Norliqva4,3761.7%
Sdamlo4,3761.7%
Lamictal XR4,3753.4%
Lamictal ODT4,3563.4%
Lamictal4,3533.4%
ProAir HFA4,3233.7%
Effexor XR4,3095.7%
Alprazolam XR4,2953.8%
Alprazolam4,2913.8%
Alprazolam Extended Release4,2913.8%
Hydrocodone Bitartrate And Acetaminophen4,1997.5%
Paxil CR4,1607.2%
Zyrtec4,1543.5%
Cipro4,1464.4%
Hydrochlorothiazide4,1162.9%
Inzirqo4,1162.9%
Microzide4,1162.9%
Nexium4,1132.2%
Protonix Delayed-release4,0382.8%
Sertraline4,0364.0%
Pantoprazole4,0212.1%
Celebrex3,9523.1%
Ambien CR3,9324.6%
Prevacid3,9272.3%
Quetiapine Fumarate3,9253.8%
Citalopram3,9123.7%
Naproxen3,7864.3%

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