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Numbness (Hypoaesthesia): Drugs With FDA Adverse Event Reports

114 medications where numbness is among the most-reported events, ranked by number of reports.

These are medications for which numbness appears among the most-reported events in FDA adverse event reports. A report does not mean the drug caused the event. Report counts largely reflect how widely a drug is used and how often events are reported; they cannot be used to compare or rank drugs by risk. This list shows drugs where this event is among their top reported reactions, not every drug ever associated with it. This information is not medical advice. Do not stop or change a medication based on this data; discuss any concerns with your healthcare provider. Data from the FDA Adverse Event Monitoring System (AEMS), formerly FAERS, via OpenFDA.

Reduced sense of touch or numbness in part of the body. Also spelled hypoesthesia in American English. Full definition in the glossary →

114 drugs meet the threshold; showing the 100 most-reported.

Medications with FDA adverse event reports of numbness, by report count
DrugReports of this event% of drug's total reports
Vitamin D8,4102.2%
Neurontin6,5421.9%
Lyrica6,3422.4%
Tysabri5,4153.0%
Gralise5,0671.7%
Gabapentin5,0311.8%
Gabarone5,0311.8%
Celebrex4,1503.2%
Avonex3,9062.7%
Naproxen3,8144.4%
Gilenya3,6654.5%
Quality Choice3,5393.2%
Ag-x3,5162.4%
Ativan3,3681.9%
Aubagio3,1707.1%
Tecfidera2,9482.4%
Vitamin C Serum2,9423.3%
Cortisone2,7823.4%
Naprosyn2,7683.6%
Adalimumab2,6916.3%
Otezla2,6651.9%
Cymbalta2,4301.8%
Baclofen (intrathecal)2,3582.8%
Aleve Back And Muscle Pain2,3363.5%
Aleve2,3353.6%
Aleve Caplets2,3353.6%
Aleve Easy Open Arthritis Cap2,3353.6%
Aleve Gelcaps2,3353.6%
Tums Ultra2,3323.7%
Lioresal (baclofen)2,3162.8%
Baclofen2,3152.8%
Fleqsuvy2,3152.8%
Lyvispah2,3152.8%
Ozobax DS2,3152.8%
Topamax2,3022.6%
Tums Regular Strength2,2423.6%
Tums Ex2,2383.6%
Tums Naturals2,2253.6%
Tums Smoothies2,2253.6%
Tums2,2243.6%
Tums Chewy Delights2,2243.6%
Tums Extra Strength Sugar-free2,2243.6%
Tums Extra Strength, Smoothies2,2243.6%
Cipro2,1982.3%
Ampyra2,0012.8%
Omegaven1,9632.2%
Cortef1,9562.9%
Cortizone 101,9162.9%
Lyrica CR1,8952.5%
Vibramycin1,8932.9%
Rolaids Power Chews 10001,8923.9%
Pregabalin1,8882.5%
Pregabalin Extended Release1,8882.5%
Calcium Carbonate1,8844.1%
Alka-seltzer Heartburn Reliefchews1,8774.1%
Pepto Kids1,8774.1%
Alka-seltzer Cool Action Extra Strength Reliefchews Mint1,8764.1%
Alka-seltzer Heartburn Relief Peppermint1,8764.1%
D-cal1,8764.1%
Doxycycline1,8762.9%
Doxycycline Hyclate1,8762.9%
Celecoxib1,7365.1%
Elyxyb - Celecoxib1,7365.1%
Rebif1,6433.5%
Ciprofloxacin1,6422.2%
Ocrevus1,6012.6%
Copaxone1,5923.0%
Ciprofloxacin In Dextrose1,5352.2%
Ciprofloxacin Otic1,5352.2%
Aimovig1,4852.8%
Zoloft1,4771.4%
Meloxicam1,4682.6%
Mobic1,4682.6%
Conzip1,4023.8%
Tramadol Hydrochloride1,4023.8%
Tramadol Hydrochloride Extended-release1,4023.8%
Ambien CR1,3951.6%
Kesimpta1,3794.3%
Ambien1,3441.7%
Xeloda1,2421.4%
Kenalog1,2404.2%
Flexeril1,1732.4%
Butrans1,0331.2%
Percocet9601.1%
Velcade9161.0%
Flagyl9101.5%
Calcium Gluconate8477.2%
Nexplanon7971.7%
Provigil6822.1%
Cardizem6783.0%
Betaseron6733.5%
Imitrex6611.8%
Strattera6602.8%
Xtandi6251.1%
Arimidex6001.7%
Adderall5471.6%
Zanaflex5162.9%
Thalomid4931.4%
Yaz4251.4%
Soma3982.1%

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