These are medications for which indigestion appears among the most-reported events in FDA adverse event reports. A report does not mean the drug caused the event. Report counts largely reflect how widely a drug is used and how often events are reported; they cannot be used to compare or rank drugs by risk. This list shows drugs where this event is among their top reported reactions, not every drug ever associated with it. This information is not medical advice. Do not stop or change a medication based on this data; discuss any concerns with your healthcare provider. Data from the FDA Adverse Event Monitoring System (AEMS), formerly FAERS, via OpenFDA.

The medical term for indigestion, meaning discomfort or pain in the upper belly, often after eating. Full definition in the glossary →

Medications with FDA adverse event reports of indigestion, by report count
DrugReports of this event% of drug's total reports
Nexium5,7733.2%
Tums Ultra2,3203.7%
Tums Ex2,2573.6%
Tums Smoothies2,2463.6%
Tums Regular Strength2,2423.6%
Tums Extra Strength, Smoothies2,2373.6%
Prilosec2,2362.1%
Tums2,2363.6%
Tums Chewy Delights2,2363.6%
Tums Extra Strength Sugar-free2,2363.6%
Tums Naturals2,2363.6%
Tecfidera1,8001.5%
Pradaxa1,5432.1%
Trulicity1,4841.7%
Pepcid1,4711.4%
Ozempic1,4382.3%
Byetta1,3762.6%
Mounjaro1,3181.5%
Mounjaro Kwikpen1,3181.5%
Esbriet1,1702.9%
Prilosec Otc1,0073.3%
Nexium 24hr9772.4%
Zepbound9321.7%
Zepbound Kwikpen9321.7%
Sutent8342.1%
Imodium A-d7081.6%
Victoza6631.6%
Nicorette Mint6303.0%
Nicorette White Ice Mint5893.0%
Nicorette Fruit Chill5833.0%
Nicorette Cinnamon Surge5773.0%
Nicorette Spearmint Burst5743.0%
Nicorette5733.0%
Nicorette Original5733.0%
Nicorette Peppermint5733.0%
Yaz5271.7%
Imodium Multi-symptom Relief4781.5%
Yasmin4201.7%
Wegovy3321.7%
VESIcare3241.3%
Vesicare Ls3241.3%
Bactroban2862.2%
Harvoni2571.3%
Lovaza2421.6%
Excedrin Migraine2161.3%
Alli1840.8%
Tykerb1841.2%
Renvela1811.6%
Rybelsus1452.1%

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